HPMC for plant capsules

The capsule has high transparency and good color.
Good formability and solidity after dipping in glue, which is more conducive to demoulding.
The capsule shell has uniform thickness and good toughness.
It does not contain chloroethanol, and the heavy metal indicators meet the requirements of the United States and European Pharmacopoeia

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Product Details

HPMC (Hydroxypropyl methylcellulose) Capsules are two-piece capsules made from cellulosic raw materials that satisfy vegetarian, religion, cultural and policy needs. These vegetable capsules are an attractive, all-natural dosage form that retain all the advantages - easy to swallow, effectively mask taste and odor, and allow product visibility. HPMC capsules are also starch-free, gluten-free and preservative-free, and meet the strict dietary needs of customers that choose a vegetarian lifestyle. HPMC capsules have been developed for both Health Supplements products and Nutraceutical.

Formula HPMC Specification

Hydroxypropyl Methylcellulose for Plant Capsules

(n-2)/2

OR=-OH、-OCH3、-[OCH2CH(CH3)]nOH or-[OCH2CH(CH3)]OCH3

Plant Capsule Specification

Item			Results
Tightness		grain	≤1
Friability		grain	≤2
Disintegration time limit		min	≤15
Burning residue	Transparent	%	≤2
	Semitransparent	%	≤4
	Opaque	%	≤6
Loss on drying		%	≤8
Heavy metal		ppm	≤10
Arsenic salt		ppm	≤2
Microbial Limit	Total number of aerobic bacteria	cfu/g	≤1000
	Total Mold and Yeast	cfu/g	≤100
	Escherichia coli	cfu/g	Not checked out
	Total Staphylococcus aureus	cfu/g	Not checked out

HPMC Specification

Item			Results
Viscosity	ML-E3	cp	2.4～3.5
	ML-E4	cp	3.6～4.5
	ML-E5	cp	4.6～5.5
pH			5.5～7.5
Insoluble matter in water		%	＜0.4
Loss on drying		%	≤4.5
Burning residue		%	＜1.2
Heavy metal		ppm	＜10
Arsenic salt		ppm	＜2
Methoxy（2910）		%	28.0～30.0
Hydroxypropyl（2910）		%	7.0～12.0
Microbial Limit	Total number of aerobic bacteria	cfu/g	≤600
	Total Mold and Yeast	cfu/g	≤60
	Escherichia coli	cfu/g	Not checked out