Hydroxypropyl Methylcellulose for Plant Capsules

Quick Details

Feature：low chromium content, high light transmission, good whiteness and low ash content.

Function：Contain Methoxyl and Hydrooxypropoxyl which are stable chemically will not react with the drug materials.

Net weight : 25kg/bag

Supply Time: All The Year

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Product Details

Hydroxypropyl Methylcellulose is a product mainly designed for the manufacturing of hydroxypropylene cellulose plant capsules. Compared with different hydroxypropylene cellulose, Hydroxypropyl methylcellulose Capsule Grade has the blessings of low chromium content, excessive mild transmission, excellent whiteness and occasional ash content. It will not react with the drug materials.

Formula HPMC Specification

Hydroxypropyl Methylcellulose for Plant Capsules

(n-2)/2

OR=-OH、-OCH3、-[OCH2CH(CH3)]nOH or-[OCH2CH(CH3)]OCH3

Plant Capsule Specification

Item			Results
Tightness		grain	≤1
Friability		grain	≤2
Disintegration time limit		min	≤15
Burning residue	Transparent	%	≤2
	Semitransparent	%	≤4
	Opaque	%	≤6
Loss on drying		%	≤8
Heavy metal		ppm	≤10
Arsenic salt		ppm	≤2
Microbial Limit	Total number of aerobic bacteria	cfu/g	≤1000
	Total Mold and Yeast	cfu/g	≤100
	Escherichia coli	cfu/g	Not checked out
	Total Staphylococcus aureus	cfu/g	Not checked out

HPMC Specification

Item			Results
Viscosity	ML-E3	cp	2.4～3.5
	ML-E4	cp	3.6～4.5
	ML-E5	cp	4.6～5.5
pH			5.5～7.5
Insoluble matter in water		%	＜0.4
Loss on drying		%	≤4.5
Burning residue		%	＜1.2
Heavy metal		ppm	＜10
Arsenic salt		ppm	＜2
Methoxy（2910）		%	28.0～30.0
Hydroxypropyl（2910）		%	7.0～12.0
Microbial Limit	Total number of aerobic bacteria	cfu/g	≤600
	Total Mold and Yeast	cfu/g	≤60
	Escherichia coli	cfu/g	Not checked out